There’s a load of science going on looking into this. Our bodies developed with gravity, so without it, they change. One example is your bone strength changes, but there are loads of other changes that go on, and many of them are not very good for you.
NASA have a really cool fact filled page on this: http://www.nasa.gov/hrp/bodyinspace They also talk about the mind, and how living in space affects how you think.
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